management of 2, 4- dichlorophenoxyacetic acid intoxication by hemodialysis: a case report
نویسندگان
چکیده
background: the herbicide 2, 4-dichlorophenoxyacetic acid (2, 4-d) can cause moderate to lethal poisoning. although urine alkalization has been recommended as the main treatment, hemodialysis (hd) may be more effective in severe cases. case: on 24th june 2014, a 53- year-old man ingested a high amount of 40% 2, 4-d. he suffered from mouth and epigastric burning sensation, vomiting and nausea. he was treated, in emam reza’s hospital of mashhad university of medical sciences, mashhad , iran, with maintenance daily fluid infusion plus 10 meq/l nahco3. up to 9 hours after exposure, he became progressively stuporous. he developed diarrhea and hypotension, bp=100/60, unresponsive to volume replacement therapy. he received regular hemodialysis (hd) with bicarbonate for three hours. at the end of hd, his blood pressure rose to 110/70 and the level of consciousness began to improve. four hours later, he was fully conscious with stable blood pressure (130/80 mmhg). conclusion: hd may be an effective, safe and fast method for 2, 4-d high dose intoxication induced coma.
منابع مشابه
Management of 2, 4- Dichlorophenoxyacetic Acid Intoxication by Hemodialysis: A Case Report
Background: The herbicide 2, 4-dichlorophenoxyacetic acid (2, 4-D) can cause moderate to lethal poisoning. Although urine alkalization has been recommended as the main treatment, hemodialysis (HD) may be more effective in severe cases. Case: On 24th June 2014, a 53- year-old man ingested a high amount of 40% 2, 4-D. He suffered from mouth and epigastric burning sensation, vomiting and nausea...
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Background: 2, 4-dichlorophenoxyacetic acid, (2, 4-D) is a selective herbicide available as the acids, esters and several salts which vary in their chemical properties, environmental behaviour, and to a lesser extent toxicity. The salt and ester forms are derivatives of the parent acid. It is widely used as a weed killer. The 2, 4-D dimethylamine is one of the salts of this group. Case Presenta...
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ETCHELLS, J. L., COSTILOW, R. N., AND BELL, T. A. 1952 Identification of yeasts from commercial cucumber fermentations in northern brining areas. Farlowia, 4, 249-264. JANSEN, E. F., AND MACDONNELL, L. R. 1945 Influence of methoxyl content of pectic substances on the action of polygalacturonase. Arch. Biochem., 8, 97-112. JANSEN, E. F., MACDONNELL, L. R., AND JANG, R. 1945 Simultaneous actions ...
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عنوان ژورنال:
iranian journal of toxicologyجلد ۱۰، شماره ۱، صفحات ۵۳-۵۵
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